KOLA, FANTA, BENZERİ ŞEKERLİ SIVILAR KULANANLAR BU YAZIYI OKUMALI SAĞLIKLI YAŞAMAK İSTEYENLER, ERKEN YAŞLANMA, KALP DAMAR HASTALIĞI VE KANSERDEN UZAK DURMAK İSTEYENLER OKUMALI
American Journal of Public Health dergisinde çıkan makaleye göre,
Soda may age you as much as smoking, study says http://ti.me/1yKOL1ovia @TIMEHealth
• Şeker aromalı sıvı içeceklerin tüketimi artıkça, hücrenin yaşlanması göstergesi olan telomeres adlı enzimde kısalması artıyor.
• Telemores enzimi insan hücrelerindeki kromozom uçlarında bulunur, hücre bölünmesi sırasında DNA stabilizasyonunu sağlarlar ve bölünmenin tamamlanmasında yardımcı olur.
• Makalenin yazarı olan bayan Elissa Epel, (PhD professor of psychiatry at University of California San Francisco), TIME dergisine verdiği röportaj’ da: Kısa telomeres; kalp damar hastalığı, erken yaşlanma, şeker hastalığı ve kanser ilişkilisin bilindiğini belirtmiş.
• Aynı zamanda bayan Elissa Epel sigara içmek ile Telemores enzimi kısaldığını belirtmiş.
• Bu çalışmada [National Health and Nutrition Examination Survey (NHANES)] 5,309 şeker, kalp damar, obesite hastalığı olmayan sağlıklı erişkin çalışmaya alınmış. Hastaların günde tükettiği yiyecekler not edilmiş ve 14 yıl boyunca denekler gözlenmiş.
• Bu çalışmanın sonuçlarına göre; 8-ounce şeker aromalı içeceğin günlük tüketim 1.9 yıl erken yaşlanmaya neden olurken, 20-ounce günlük tüketim 4.6 yıl erken yaşlanmaya neden oluyor. Yani tüketim artıkça Telemores boyutunda kısalma saptanıyor.
• Fakat tam tersi taze sıkılmış meyve suları tüketenlerde Telemores enzim boyutlarında kısalma saptanmamış. Tam tersi çalışmaya katılanlarda sıkma meyve suyu içenlerde marginal olmak ile birlikte uzama saptanmış.
• İlginç olan, diyet sıvılarda, yani karbonlu şeker barındırmayan tatlandırılmışlarda Telemores enzim boyutlarında kısalma saptanmamış.
SONUÇ: KOLA, FANTA, BENZERİ ŞEKERLİ SIVILAR KULANANLAR BU YAZIYI TEKRAR OKUMALI, ŞEKERLİ SIVILAR SİGARA GİBİ TELEMORES KISALMASI YAPARAK ERKEN YAŞLANMAYA, KALP DAMAR HSATALIĞI VE KANSERE NEDEN OLABİLMEKTEDİR.
KAYNAK:
Soda and Cell Aging: Associations Between Sugar-Sweetened Beverage Consumption and Leukocyte Telomere Length in Healthy Adults From the National Health and Nutrition Examination Surveys
Cindy W. Leung, ScD, Barbara A. Laraia, PhD, Belinda L. Needham, PhD, David H. Rehkopf, ScD, Nancy E. Adler, PhD, Jue Lin, PhD, Elizabeth H. Blackburn, PhD, and Elissa S. Epel, PhD
Cindy W. Leung is with the Center for Health and Community, School of Medicine, University of California, San Francisco. Barbara A. Laraia is with the School of Public Health, University of California, Berkeley. Belinda Needham is with the Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor. David H. Rehkopf is with the Department of Medicine, Stanford University, Palo Alto, CA. Nancy E. Adler and Elissa S. Epel are with the Center for Health and Community and the Department of Psychiatry, School of Medicine, University of California, San Francisco. Jue Lin and Elizabeth H. Blackburn are with the Department of Biochemistry and Biophysics, University of California, San Francisco.
Correspondence should be sent to Cindy W. Leung and Elissa S. Epel, Center for Health and Community, School of Medicine, University of California, San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94118 (for C. W. Leung, e-mail: cindyleung@post.harvard.edu; for E. S. Epel, e-mail: eepel@lppi.ucsf.edu). Reprints can be ordered at http://www.ajph.org.sci-hub.org by clicking the “Reprints” link.
Contributors
C. W. Leung, B. A. Laraia, B. L. Needham, D. H. Rehkpof, and E. S. Epel conceptualized the study. C. W. Leung, B. L. Needham, D. H. Rekhopf, and E. S. Epel analyzed the data. J. Lin and E. H. Blackburn performed the telomere assay. C. W. Leung wrote the first draft of the article. All authors contributed to the interpretation of the results, made substantial revisions to the content, and approved the final article.
Peer Reviewed
ABSTRACT
Objectives. We tested whether leukocyte telomere length maintenance, which underlies healthy cellular aging, provides a link between sugar-sweetened beverage (SSB) consumption and the risk of cardiometabolic disease.
Methods. We examined cross-sectional associations between the consumption of SSBs, diet soda, and fruit juice and telomere length in a nationally representative sample of healthy adults. The study population included 5309 US adults, aged 20 to 65 years, with no history of diabetes or cardiovascular disease, from the 1999 to 2002 National Health and Nutrition Examination Surveys. Leukocyte telomere length was assayed from DNA specimens. Diet was assessed using 24-hour dietary recalls. Associations were examined using multivariate linear regression for the outcome of log-transformed telomere length.
Results. After adjustment for sociodemographic and health-related characteristics, sugar-sweetened soda consumption was associated with shorter telomeres (b = –0.010; 95% confidence interval [CI] = −0.020, −0.001; P = .04). Consumption of 100% fruit juice was marginally associated with longer telomeres (b = 0.016; 95% CI = −0.000, 0.033; P = .05). No significant associations were observed between consumption of diet sodas or noncarbonated SSBs and telomere length.
Conclusions. Regular consumption of sugar-sweetened sodas might influence metabolic disease development through accelerated cell aging.
Read More: http://ajph.aphapublications.org.sci-hub.org/doi/abs/10.2105/AJPH.2014.302151
